All samples leaving the site should be accompanied by what?

• A. Chain-of-Custody form
• B. Chain-of-Custody record
• C. Sample logbook
• D. Delivery manifest

Answer: (B)

The main idea is to maintain traceability and integrity of samples as they leave a site. A chain-of-custody record is the formal documentation that travels with the sample, listing every person who handles it, the times of transfer, locations, and any condition notes. This unbroken record ensures no tampering or misidentification occurs and lets the lab and any regulators verify who had possession of the sample at each step, which is essential for defensible results and proper data quality.

A logbook is typically an internal site record that may not accompany the sample or capture the complete custody history. A delivery manifest documents shipment details but doesn’t provide the full custody trail. A chain-of-custody form is closely related, but the test emphasis is on the formal record that accompanies the sample during transport, which is why the chain-of-custody record is the best fit.